Hypertension Nursing Diagnosis 6 Care Plans for Any Patient

Hypertension Nursing Diagnosis 6 Care Plans for Any Patient SAT / ACT Prep Online Guides and Tips Hypertension, or high blood pressure, is an issue that affects millions of people around the world. If not properly treated, hypertension can lead to serious issues, including heart attack or stroke. That means it’s imperative to have an accurate nursing diagnosis for hypertension as well as an effective care plan. After explaining what hypertension is, what causes it, and what common symptoms are, this guide explains six key hypertension nursing diagnoses. For each diagnosis, the NANDA definition, potential evidence, and desired outcomes are explained, as well as steps to take for the nursing intervention. Nursing Diagnosis for Hypertension: What Is It? Normal blood pressure is when blood pressure is lower than 120/80 mmHg most of the time. A patient is diagnosed with hypertension, the medical term for high blood pressure, when their blood pressure is 140/90 mmHg most of the time. There are several levels of hypertension: Normal Blood Pressure: Lower than 120/ 80 Prehypertension: 120-139/80-89 Stage 1 Hypertension: 140-159/90-99 Stage 2 Hypertension: 160+/100+ Hypertension can be dangerous because it can make the heart work harder to pump blood to the body, which can increase the risk of heart failure, stroke, and hardening of the arteries. What Causes Hypertension? The exact cause of hypertension is not often known. Primary (or essential) hypertension is when hypertension has no known cause, or there is no evidence to link it to a specific cause. Primary hypertension makes up about 90% of all hypertension cases. Secondary hypertension is high blood pressure that does have an identifiable cause. Potential causes of hypertension (primary or secondary) include: Being overweight or obese Smoking Genetics/family history of hypertension A diet high in salt Consuming more than 1-2 alcoholic drinks a day Stress Old age Lack of exercise Sleep apnea Kidney disease Thyroid disorders Signs and Symptoms of Hypertension Hypertension does not always cause symptoms; in fact, about a third of people who have hypertension don’t know they have it because of no or few symptoms. Below are some of the most common symptoms of hypertension: Headache Ringing or buzzing in the ears Fatigue Irregular heartbeat Confusion or dizziness Nosebleed Blurred vision Difficulty breathing Chest pain Blood in the urine Nursing Care Plans for Hypertension Once a patient is found to have high blood pressure, it’s important to follow the appropriate nursing diagnosis and nursing care plan for hypertension in order to reduce the effects of hypertension and keep the patient’s health and quality of life high. Below are six nursing care plans for hypertension. These six care plans cover the main issues associated with hypertension. Each one includes its own nursing diagnosis, NANDA definition, possible signs of evidence, desired outcome, and nursing interventions. Use the NANDA definition and potential evidence to determine the correct nursing care plan for hypertension. Some patients may require multiple care plans. Hypertension Nursing Diagnosis #1: Risk for Decreased Cardiac Output NANDA Definition: Inadequate blood pumped by the heart to meet metabolic demands of the body. Possibly Evidenced By: N/A. This intervention is used to in order to prevent decreased cardiac output from occurring. Desired Outcomes: Show stable cardiac rhythm and rate. Maintain blood pressure within an acceptable range. Participate in activities that lower blood pressure and cardiac load. Interventions: Check patient’s lab data (cardiac markers, blood cell count, electrolytes, ABGs, etc.) to determine contributing factors. Monitor and record blood pressure in both arms and thighs Measure blood pressure in both hands. Auscultation of breath sounds and heart rhythm. Observe patient’s skin color, temperature, and capillary refill time. Advise the patient on reducing sodium intake, if needed. Administer medication, if needed. Hypertension Nursing Diagnosis #2: Acute Pain (Typically Headache) NANDA Definition: Pain is whatever the experiencing person says it is, existing whenever the person says it does; an unpleasant sensory and emotional experience arising from actual or potential tissue damage or described in terms of such damage sudden or slow onset of any intensity from mild to severe with an anticipated or predictable end and a duration of. Possibly Evidenced By: Patient reports throbbing pain in head, most often upon awakening. Changes in appetite. Patient reports neck stiffness, blurred vision, dizziness, nausea, and/or vomiting. Desired Outcomes: Patient states they are no longer suffering from a headache and appear comfortable and pain-free. Interventions: Determine the specifics of the pain, such as intensity, where it is located, and how long it has been going on. Note the patient’s attitude towards pain and any history of substance abuse. Encourage rest during severe pain episodes. Recommend methods of relief, such as neck and back rubs, applying cool cloths to the forehead, and avoiding bright lights. Limit how much the patient moves around. Provide medication, if needed. Hypertension Nursing Diagnosis #3: Activity Intolerance NANDA Definition: Insufficient physiological or psychological energy to endure or complete required or desired daily activities. Possibly Evidenced By: Patient reporting weakness or fatigue. Abnormal heart rate as a result of activity. Exertional discomfort or dyspnea. Electrocardiogram (ECG) changes reflecting ischemia; dysrhythmias. Desired Outcomes: Patient participates in necessary and/or desired activities. Uses identified techniques to enhance activity tolerance. Reports a measurable increase in his/her tolerance for activity. Demonstrates a decrease in noticeable signs of intolerance. Interventions: Note each of the factors that contribute to fatigue (age, health, illness, etc.). Evaluate the patient’s degree of activity intolerance and when it occurs. Monitor how the patient responds to activity (pulse, heart rate, chest pain, dizziness, excessive fatigue, etc.). Explain energy conserving techniques (shower chairs, sitting to brush teeth, etc.). Assess any emotional factors that may be contributing to activity intolerance (such as depression or anxiety). Encourage the patient to engage in self-care and progressive activity when possible. Hypertension Nursing Diagnosis #4: Ineffective Coping NANDA Definition: Inability to form a valid appraisal of the stressors, inadequate choices of practiced responses, and/or inability to use available resources. Possibly Evidenced By: Patient states he/she is unable to cope; patient asks for help. Worry, irritability, anxiety, and/or depression as a result of hypertension diagnosis. Destructive behavior such as overeating, lack of appetite; excessive smoking/drinking, and/or alcohol abuse Desired Outcomes: Patient can identify his/her ineffective coping techniques and their consequences. Verbalizes awareness of own coping abilities. Identifies potentially stressful situations and takes steps to avoid or modify them. Shows the use of effective coping skills. Interventions: Determine what specific areas the patient has difficulty coping with. Assess the effectiveness of the patient’s current coping skills and where improvements can be made. Help the patient identify specific stressors and how to cope with them. Work with the patient to develop a care plan, and encourage participation in the plan. Help the patient identify and begin planning for necessary lifestyle changes. Encourage the patient to evaluate his/her priorities and goals in life. Hypertension Nursing Diagnosis #5: Imbalanced Nutrition (More Than Body Requirements) NANDA Definition: Intake of nutrients that exceeds metabolic needs. Possibly Evidenced By: Patient’s weight is 10%–20% more than ideal his/her height and frame. Reported or observed dysfunctional eating patterns. Desired Outcomes: Patient understands the relationship between hypertension and obesity. Initiates/maintains an appropriate exercise program. Shows changes in eating patterns, such as food choice and/or quantity, to attain a healthier body weight. Interventions: Assess the patient’s understanding of the relationship between hypertension and obesity. Discuss the relationship between hypertension and obesity with the patient. Discuss the need for a decreased caloric intake, as well as a limited intake of salt, sugar, and fat. Determine the patient’s desire to lose weight. Help the patient establish a realistic exercise plan. Help the patient establish a realistic nutrition plan. Refer the patient to a nutritionist, if needed. Hypertension Nursing Diagnosis #6: Knowledge Deficit NANDA Definition: Absence or deficiency of cognitive information related to a specific topic. Possibly Evidenced By: Verbalization of the problem. Patient requires information or more information, or he/she doesn’t understand the information given. Patient inaccurately follows instructions. Patient appears agitated, hostile, or upset when the condition and ways for managing it are discussed. Desired Outcomes: Patient can express his/her knowledge of the management and treatment of hypertension. Patient correctly uses the drugs they are prescribed and understand their side effects. Interventions: Determine what information the patient currently understands. Assess readiness and blocks to learning. Include the patient’s partner, if possible. Describe the nature of hypertension, how it affects different parts of the body, and how it can be treated. Avoid using the term â€Å"normal BP†. Instead use the term â€Å"well-controlled† to describe patient’s BP within desired limits. Discuss with the patient changes he/she can make in order to manage hypertension. Discuss the importance of maintaining a stable weight. Discuss the need for low-calorie diet, low in sodium to order. Help the patient create a schedule for taking medications. Direct the patient to other resources that can be used to better understand and manage hypertension. Review: Diagnosing and Treating Hypertension Hypertension, the medical term for high blood pressure, is an issue that can have serious and long-term health effects if it isn’t properly managed. Therefore, having an effective nursing care plan for hypertension is important. While it’s often difficult to pinpoint the cause of hypertension, high blood pressure may be caused by the weight, smoking, high sodium intake, and/or genetics, as well as other factors. Some symptoms of hypertension can include headache, dizziness, fatigue, difficulty breathing, and/or chest pain, although some patients with hypertension don’t show any symptoms. There are six key nursing diagnoses for hypertension. Risk for decreased cardiac output Acute pain (typically headache) Activity intolerance Ineffective coping Imbalanced nutrition (more than body requirements) Knowledge deficit For each nursing diagnosis for hypertension, it’s important to know the NANDA definition, possible signs of evidence, desired outcome, and nursing interventions. What's Next? Thinking about exploring a career in healthcare administration? Read our complete guide to getting a healthcare administration degree, with explanations for what levels of qualification you need for different careers.

SAT Chemistry Subject Test Information

SAT Chemistry Subject Test Information    You dont have to be going into the chemistry field in college to take the SAT Chemistry Subject Test. If youre thinking about heading into pharmacology, medicine, engineering or biology, then this SAT Subject Test could show off your skills when others cant. Lets get into whats on this exam, shall we? Note: This test is not part of the SAT Reasoning Test, the popular college admissions exam. This is one of the many SAT Subject Tests, exams designed to showcase your particular talents in all sorts of fields. SAT Chemistry Subject Tests Basics Before you register for this test, here are the basics: 60 minutes85 multiple-choice questions200-800 points possibleA period table will be provided for you.Calculators are not permitted on the test, but are unnecessary anyway. SAT Chemistry Subject Test Content So, what will you need to know? Here are the number of questions and the types of content youll be looking at when you sit for the exam: Structure of Matter: Approximately 21-22 questions Atomic Structure: (experimental evidence of atomic structure, quantum numbers and energy levels, electron configurations, periodic trends)Molecular Structure: (Lewis structures, three-dimensional molecular shapes, polarity)Bonding: (ionic, covalent, and metallic bonds, relationships of bonding to properties and structures; intermolecular forces such as hydrogen bonding, dipole-dipole forces, dispersion (London) forces) States of Matter: Approximately 13 – 14 questions Gases: (kinetic molecular theory, gas law relationships, molar volumes, density, and stoichiometry)Liquids and Solids: (intermolecular forces in liquids and solids, types of solids, phase changes, and phase diagrams)Solutions: (molarity and percent by mass concentrations, solution preparation and stoichiometry, factors affecting solubility of solids, liquids, and gases, qualitative aspects of colligative properties) Reaction Types: Approximately 11 – 12 questions Acids and Bases: (Brà ¸nsted-Lowry theory, strong and weak acids and bases, pH, titrations, indicators)Oxidation-Reduction: (recognition of oxidation-reduction reactions, combustion, oxidation numbers, use of activity series)Precipitation: (basic solubility rules) Stoichiometry: Approximately 11 – 12 questions Mole Concept: (molar mass, Avogadro’s number, empirical and molecular formulas)Chemical Equations: (balancing of equations, stoichiometric calculations, percent yield, and limiting reactants) Equilibrium and Reaction Rates: Approximately 4 – 5 questions Equilibrium Systems: (LeChà ¢teliers principle in gaseous and aqueous systems, equilibrium constants, and equilibrium expressions)Rates of Reactions: (factors affecting reaction rates, potential energy diagrams, activation energies) Thermochemistry: Approximately 5 – 6 questions Conservation of energy, calorimetry and specific heats, enthalpy (heat) changes associated with phase changes and chemical reactions, heating and cooling curves, entropy Descriptive Chemistry: Approximately 10 – 11 questions Common elements, nomenclature of ions and compounds, periodic trends in chemical and physical properties of the elements, reactivity of elements and prediction of products of chemical reactions, examples of simple organic compounds and compounds of environmental concern Laboratory Knowledge: Approximately 6 – 7 questions Knowledge of laboratory equipment, measurements, procedures, observations, safety, calculations, data analysis, interpretation of graphical data, drawing conclusions from observations and data SAT Chemistry Subject Test Skills Recall of Facts: 17 Questions. Here, youll be tested on whether or not you remember a definition, can identify a term, or can otherwise shell out important chemistry knowledge. Application of Material: 39 Questions. This is where things get tougher. Can you apply the knowledge youve learned to solve chemistry problems? Can you apply the concepts of ratios and proportions to solve basic word problems without the use of your calculator? Synthesis of Material: 29 Questions. This skill is the toughest of the three. Here, youll need to be able to make assertions and create new ideas based on information presented. Why Take the SAT Chemistry Subject Test? Obviously, no one is going to take this test if it doesnt fit in with his or her major, unless youve really done poorly on the regular SAT Test and want to redeem yourself a bit by showing that you do have some brains in the old noggin. If you are majoring in a chemistry-related field like medicine, pharmacology, any of the sciences, then take it to show what you can do and emphasize the positive impact you can make on the program. Competition is fierce for some of these majors, so its great to put your best foot forward. Besides, it just may be a requirement for your program, so be sure to check with your admissions advisor before you blow this off. How to Prepare for the SAT Chemistry Subject Test The College Board recommends taking at least 1 year of a college-prep Chemistry course, along with having a year in Algebra (which everyone does) and some laboratory work. Personally, I recommend getting a test prep book for this bad boy and learning anything you didnt when you were distracted by all the beakers in high school Chemistry class. In addition, there are some free practice questions on the College Board site, along with the answers to show you where you may have tripped up. Sample SAT Chemistry Subject Test Question The hydrogen ion concentration of a solution prepared by diluting 50. mL of 0.10 M HNO3(aq) with water to 500. mL of solution is? (A) 0.0010 M(B) 0.0050 M(C) 0.010 M(D) 0.050 M(E) 1.0 M Answer: Choice (C) is correct. This is a question that concerns the concentration of a diluted solution. One way to solve the problem is through the use of ratios. In this question, a solution of nitric acid is diluted 10-fold; therefore, the concentration of the solution will decrease by a factor of 10, that is, from 0.100 molar to 0.010 molar. Alternatively, you could calculate the number of moles of H ions present and divide this value by 0.50 liter: (0.100 Ãâ€" 0.050)/0.5 M of the diluted solution. Good Luck!

Social Capital Research Paper Example | Topics and Well Written Essays - 1000 words

Social Capital - Research Paper Example A review of the additional literature, in addition to the source article, will provide collaborative details to provide support for the conclusion established. The case study by Chenhall, Hall, & Smith examined how elements of a management control system can either enhance or inhibit the bonding and bridging dimensions of social capital with potential consequences on both economic and cultural capital (2010, p.2). The study attempts to highlight and provide data to support the notion that management control systems can be contradictory as they relate to social capital. The concept of social capital is used to outline a distinctive approach to understanding the relationship between management control systems and the development of social connections in and between organizations (Chenhall, Hall, & Smith, 2010). The study additionally illustrates how formal belief systems and operational controls sustain strong interior relationships and also help to establish the case organization†™s standing with peripheral organizations vital to external bridging (Chenhall, Hall, & Smith, 2010). However, there are also several limitations to the relevancies demonstrated by the study. The study was based on a limited number of interviews rather than in-depth observational data (Chenhall, Hall, & Smith, 2010). Additionally, the study indicates that efforts to use â€Å"financial controls interactively† to deal with issues of cost awareness were not successful due to the fact that they were interpreted as â€Å"incompatible† with natural advancements and threatened to bond (Chenhall, Hall, & Smith, 2010, p.2). Literature Review Social capital can be measured in a variety of ways, although obtaining a "true", definitive measurement is not possible (What is, 2011). The most popular definitions of social capital are multidimensional and incorporate numerous aspects of analysis into a comprehensive framework (What is, 2011). Attempts to measure the properties of â €Å"inherently ambiguous concepts† such as "community", "network" and "organization" has caused problems in establishing the concept of social capital (What is, 2011). Although a few long-standing surveys have been designed to gauge "social capital", they have left researchers to assemble indexes from a range of items, like â€Å"measures of trust in government, voting trends, memberships in civic organizations, and hours spent volunteering† (What is, 2011). Researchers are attempting to compile new surveys that will give the concept of social capital a more definitive meaning. There are several examples of social capital, like civic organizations, community organizations, and scholastic communities that can significantly contribute to the overall organizational platform.

The UAE Essay Example | Topics and Well Written Essays - 1000 words

The UAE - Essay Example Moreover, it was recently ranked number 40 out of the 183 countries with regard to the overall ease of conducting business. This article explores the business environment of the UAE by examining its PESTL environments. The United Arabs Emirates (UEA) is a Middle East country bordering the Arabian Gulf and Oman Gulf, between Saudi Arabia and Oman. It is a federation of seven countries established in 1971with its members operating under one federal government. The country which is a monarchy is politically stable. Even though democracy sometimes is jeopardized, citizens enjoy a lot of freedom. UAE has four levels of governments: President, Federal National Council, High Council, and Local Emirs. What is evident is that most powers are vested in the hands of the Emirs. As such, no authority is allowed beyond Emirs, implying that citizens from different Emirates have absolutely no say on political issues (Kjeilen 2004). The UAE enjoys favorable diplomatic relations with several countries. It has close ties with most Arab countries including Egypt and Pakistan. The country’s main export markets include Germany and the United Kingdom even as the U.S. and France maintain security related cooperation with the country. The government has made great effort to increase spending on job creation, opening up space for private investor involvement as well as expanding its infrastructural facilities to create a favorable environment for business and investment. The government’s commitment to promote business and investment is also seen when it created a free trade zone in UAE. The zone was mainly established by the government as a way of promoting direct foreign investment in the country. This implies that there are no limits on overseas ownership within UAE. The government in this case allows foreign investors to establish fully-owned companies within the free trade zones, which currently stand at

Media Coursework Report Essay Example for Free

Media Coursework Report Essay For my AS Media coursework, I chose to use fashion as the genre of my magazine. To help with my pre-production, I had to perform my own qualitative and quantitative research into fashion magazines and find out what my target audience of 15-19 year old girls would want from it. I went on to create the preliminary products which included the front cover and contents page, and from these the main products which were the alternative front cover and double page spread. These were all produced using Photoshop. I began by creating a questionnaire, as this is an effective way of finding out what my target audience will be looking for in a fashion magazine. I included 8 questions which asked some general questions into what the participant is interested in, and some into what they would like to see in a fashion magazine, to help me create my front cover and contents page. I gave 20 questionnaires out to other students aged 16-19 as this fits my target audience. By analysing the results of the questionnaire, I found out a range of information to help my design my front cover. The participants chose  £2.50 as the appropriate price and for the magazine to be produced monthly, which I will apply when creating the front cover. 80% of participants said they would be more likely to pick up the magazine if there was a celebrity on the cover. Therefore, I will ask a friend to pose as a celebrity to make it more appealing to my target audience. 50% of participants wanted to see interviews in the magazine and 30% wanted genre-specific features (in this case, it will be fashion, clothes etc.) which I will make sure to include in the contents page. I formed a focus group with other AS Media students in my class. They were all females, ranged from the ages 16-17, and had an interest in fashion, making them representative of my target audience. I asked them if I should put just one image on the front cover, or add smaller ones around the page to show what’s included inside. The feedback I received was very helpful, and led me to use just the one main photo for my preliminary front cover and  my main front cover, to keep the brand consistent. This keeps it looking professional and stops the page from looking overcrowded and trashy. By textually analysing fashion magazines currently on the market, I discovered a recurring theme among them. The bigger magazines (Vogue, Elle) have been around for much longer, and their cover stars overlap the masthead. However, when analysing Look, I noticed that the masthead overlapped the cover star, suggesting that this magazine is new and lesser known. From this, I decided to have the whole masthead of my magazine visible by audiences for my preliminary front cover as it is new and allows audiences to recognise the brand in future. I then chose to overlap part of the masthead on my main front cover with the cover star, as it is a later issue and audiences should then be able to recognise it. The content analysis allowed me to see what’s included in fashion magazines. This helped when compiling the contents page. Obviously the main part of a fashion magazine is the fashion itself. However, it also includes items related to hair and beauty, interviews, articles, advice and special features. I made sure to include all of these when designing my contents page, but I chose to keep the main focus on fashion. I decided to target my magazine towards teenage girls aged between 15 and 19. I thought this was a good range, as girls in their teens will have a more developed sense of style. From my institutional research, I discovered that many fashion magazines were targeted towards women in their 20s and 30s, and decided to aim mine at a teenage audience. Audiences for fashion magazines such as Vogue and Elle were predominantly female; therefore it was important to include items in the contents and on the cover that would attract a female audience. I also tried to use feminine colours where appropriate in the magazine to indicate the target audience. I also made sure my focus group was a good representation of my target audience, thus making sure they had a clear interest in fashion and fit the age category, which they did. I created my preliminary and main products using Adobe Photoshop which had all the necessary tools I needed to create a realistic and professional  magazine. By comparing my magazine in relation to Vogue, I am able to see the strengths and weaknesses of my production. I began by selecting the images I would use for each page. I used a Fujifilm Finepix S2950 to capture the photos. The models used direct mode of address as this is the most effective way of attracting the audience. I used a hairdryer to create the effect of wind blowing the model’s hair. I chose to use an image with a light background, with a model wearing spring clothing. I think this helped to make the cover look more professional as Vogue often incorporates the colours of the magazine to fit the season. I increased the contrast of the image to make it look brighter and more appealing. I then went on to create puffs around the image, and used only ‘Century Gothic’ font to keep it simple and sophisticated. I used a dark blue for the text as it contrasted well with the pink clothing that the model wore. I made sure to include small details as well, including the bar code, price and date to make the product more realistic. I was very pleased with the outcome of my preliminary front cover as it looked professional in relation to magazines on the market today, and had a similar style to that of Vogue magazine. My next task was the contents page, and from the research I did I was able to see what needed to be included. I wanted to keep it consistent, and so I used the same masthead from the front cover and used it at the top of the contents page. This was used in InStyle’s contents page. I also used the same colour scheme as the front cover, to show that the two are related. I kept the text in columns and split the content into sections, which is what I noticed InStyle and Vogue did when I researched them. I also noticed in the Vogue contents page that there was some information about the front cover image, so I decided to include that in my own, with information on where to buy the clothes. I was quite pleased with the result of my contents page, as I spent a lot of time on it. However, I felt that there was too much white space that could have been filled in. It may have been a good idea to add in some borders to give the page some depth. For the alternative cover, I made sure I kept the same font style and size for my masthead. This is because it is important to keep the brand recognisable. I asked my focus group if this was a good idea and they  agreed, saying it would keep it consistent and professional. All magazines do this, but fashion magazines such as Vogue and Elle often change the colour every month to fit with the theme. I have decided to do the same in my own production, by changing the colour of the masthead and the puffs to a maroon colour, to tie in with the month and season. It also contrasted well with the cover model’s blue dress. Like Vogue, I made sure I kept three puffs around the edges of the main image, to stop them from overlapping. I am really pleased with the outcome of this as I think it could pass as a real magazine. I then went on to create the double page spread in A3 size, and selected my image to cover the whole background. This meant there was no white space left around the edges, but there was still space to put some text. I wanted the image to take up dominant space on the page to catch the reader’s eye, which is what I noticed was used in Vogue’s double page spread. I brightened the image and removed some blemishes on the model to try and reach a flawless image, as perfection is one of the main selling points for a fashion magazine. I set the text out in two columns, as this is the layout that most magazines use, including Vogue. I used ‘Rage Italic’ for the headline, which is what I used for the headline on the cover, to keep a consistent house style. I also added page numbers to the bottom corners, as these small details help to build up a realistic product. I feel that my magazine is very similar to a professional product and would stand out in the market place. It follows the codes and conventions of a typical fashion magazine, and is aesthetically pleasing for the target audience. If I were to change anything, I would make the front cover masthead slightly larger, to make it more eye-catching.

Careers in Acoustic and Audio Equipment Design :: Essays Papers

Careers in Acoustic and Audio Equipment Design Audio engineers have an interesting combination of character traits. On the one hand they tend to love music and want to have a hand in creating it. On the other hand they are also lovers of technology and ‘cool gear’. Along with an interest in technology usually comes an interest in understanding how it works – a desire to master the technology. With some people also comes a desire to go beyond the latest gear and ‘do it better’. They have a desire to create new technology which will provide the ultimate listening / processing / recording / etc experience. This paper will explore career opportunities that exist for those people. There are many different areas of audio related design in which to pursue a career. To illustrate, consider the typical live music concert. First of all, the performance venue needs to be acoustically designed to provide a good listening environment. Each of the performers’ instruments is designed and depending on the instrument the design could have involved acoustic as well as electronic knowledge. Sound reinforcement for the concert involves a myriad of equipment each with it’s own design criteria. Finally, if the concert is to be recorded and produced on a CD, all the recording equipment would need to be designed as well as the studio that it is used in. To design something is to conceive and invent. It is the art of creating the arrangement of parts or details of something. Furthermore, the point of designing something is to meet a need or to solve a defined problem. Each of the different design tasks involved in the concert scenario requires a different type of design expertise. There are basically four areas of design involved - acoustics, electronics, industrial design and mechanical design. Each of these areas overlaps with the other somewhat. Furthermore, each of these areas has an ‘art’ side and a ‘science’ side to them. Acoustic designers create the plan for performance spaces like concert halls as well as recording studios, and any other space that needs to provide a quality listening environment. They may also be involved in specifying equipment to provide sound reinforcement in the venue. Some acoustic design firms offer a full range of services, which may include site analysis, interior design, lighting, power and HVAC systems, wire management, budgeting, construction administration, and acoustic tuning (Droney).

A Phytochemical and Pharmacological Review Essay

Sambong (Blumea balsamifera) is a native flowering or weed that is endemic in the Philippines and other tropical countries. It is a popular herb especially for its healing properties including antidiarrhetic, antigastralgic, expectorant, stomachic, and antispasmodic, among others. Aside from these, sambong is also popular for being emmenagogues, or for stimulating menstruation or the blood flow in the pelvic area and uterus. As cure for menstrual cramps, the sambong leaves are boiled to create a sambong tea, which is then consumed by the patient. Aside from easing the painful cramps by facilitating menstruation, sambong also helps in cleaning the kidneys. The plant is actually especially known as a natural cleansing herb. Since the plant is emmenagogues, drinking the sambong tea is not advisable to pregnant women as well as women who wanted to be pregnant. Moreover, drinking sambong should also be regulated because it also has hallucinogenic effects when excessively consumed Blumea b alsamifera (L.) DC. (Asteraceae), also known as sambong, has been used as medicine for thousands of years in Southeast Asia countries, such as China, Malaysia, Thailand, Vietnam, and Philippines. Sambong is the most important member of the genus Blumea and is an indigenous herb oftropical and subtropical Asia, especially in China. This plant grows on forest edges, under forests, riverbeds, valleys and grasses [4,5]. In China, it is generally a common used herb in the areas south of theYangtze River, such as Hainan, Guizhou, Yunnan, and Guangdong provinces and Taiwan [6–8].B. balsamifera is commonly called â€Å"Ainaxiang† and â€Å"Dafeng’ai† in Chinese and used as incensebecause it has a high level of essential oils [9]. It was originally recorded in â€Å"Bei Ji Qian Jin YaoFang† in 652 by Sun Simiao. The whole plant or its leaves were used as a crude Chinese traditional medicinal material to treat eczema, dermatitis, beriberi, lumbago, menorrhagia, rheumatism, skininjury, and as an insecticide [10]. Bing Pian and Aipian are two important traditional Chinese medicines (TCMs) extracted from plants and have been used as one in prescriptions for centuries in China. Both of them mainly contain borneol and are similar in efficacy [11]. They are synonymous in the Chinese  pharm aceutical industry nowadays. Before 2010, sambong was one of the most important plant sources for Bing Pian, but since 2010, the Pharmacopoeia of the People’s Republic of China records B. balsamifera as the only plant source for Aipian [11], with a consistent efficacy with B.  balsamifera medicinal materials, which could induce resuscitation, clear heat, and relieve pain. Recently, extracts of its leaves have been verified do display various new physiological activities, such as antitumor , antifungal [13,15], radical-scavenging [16], and anti-obesity properties . The main active compound is L-borneol, which was characterized by a high volatility. Besides, essential oils, flavonoids, and terpenoids with several different biological activities were also reported . These studies could explain why this plant has multiple pharmacological effects. In this review, botanical descriptions, herbal authentications, and phytochemical constituents of B. balsamifera are covered. In addition, the previous in vitro and in vivo studies conducted on its biological activities are reviewed, concentrating on antitumor, hepatoprotective, superoxide radical scavenging, antioxidant, antimicrobial, anti-inflammation, antiplasmodial, antityrosinase, platelet aggregation, wound healing, anti-obesity, disease and insect resistant activities as well as enhancing percutaneous pen etration. Sambong is a half woody, strongly aromatic shrub, densely and softly hairy, 1 to 4 meters high. Stems grow up to 2.5 centimeters in diameter. Leaves are simple, alternate, elliptic- to oblong-lanceolate, 7 to 20 centimeters long, toothed at the margins, pointed or blunt at the tip, narrowing to a short petiole which are often auricled or appendaged. Flowering heads are stalked, yellow and numerous, 6 to 7 millimeters long, and borne on branches of a terminal, spreading or pyramidal leafy panicle. Discoid flowers are of two types: peripheral ones tiny, more numerous, with tubular corolla; central flowers few, large with campanulate corolla. Involucral bracts are green, narrow and hairy. Anther cells tailed at base. Fruits are achenes, dry, 1-seeded, 10-ribbed, hairy at top. – Considered anthelmintic, antidiarrheal, antigastralgic, antispasmodic, astringent, carminative, emmenagogue, expectorant, stomachic, and vulnerary.Leaves used a flavoring ingredient. Folkloric – Leaves as poultice for abscesses. – Decoction of roots and leaves for fevers, kidney stones, and cystitis. – Decoction of leaves used to induced diuresis for purpose of treating kidney stones. – Sitz-bath of boiled leaves, 500 gms to a gallon of water, for rheumatic pains of waist and back. – Used in upper and lower respiratory tract affections like sinusitis, asthmatic bronchitis, influenza. – Applied while hot over the sinuses. Used for wounds and cuts. Fresh juice of leaves to wounds and cuts. – Poultice of leaves applied to the forehead for relief of headaches. – Tea is used for colds and as an expectorant; likewise, has antispasmodic and antidiarrheal benefits. Postpartum baths. – In Vietnam, decoction of fresh leaves used for cough and influenza or as inhalation of vapour from boiling of leaves. Poultices of pounded leaves applied to hemorrhoids; an alcoholic maceration used as liniment for rheumatism. – 3% ethanol solution used to soothe itching. – In Thailand, dried leaves are chopped, made into cigarettes and smoked for treating sinusitis. – For fever, leaves boiled and when lukewarm used as sponge bath. – Decoction of roots used for fever. – Decoction of leaves, 50 gms to a pint of boiling water, 4 glasses daily, for stomach pains. – In SE Asia widely used for various women problems. Postpartum, leaves are used in hot fomentation over the uterus to induce rapid involution. Also used for menorrhagia, dysmenorrhea, functional uterine bleeding and leucorrhea. – Roots used for menorrhagia. – Decoction of roots and leaves used for rheumatism and arthritis; also used for treatment of post-partum joint pains. – Poultice of fresh leaves applied to affected joint. – In Chinese and Thai medicine, leaves used for treatment of septic wounds and other infections. – A sitz-bath of boiled leaves used in the treatment of lumbago and sciatica. – In Chinese medicine, used as carminative, stimulant, vermifuge, expectorant, and sudorific. Preparations †¢ Fever: decoction of roots; boil 2 – 4 handfuls of the leaves. Use the lukewarm decoction as a sponge bath. †¢ Headaches: apply pounded leaves on the forehead and temples. Hold in place with a clean piece of cloth. †¢ Gas distention: boil 2 tsp of the chopped leaves in 1 cup of water for 5 minutes. Drink the decoction while warm. Also used for upset stomach. †¢ Postpartum, for mothers’ bath after childbirth. †¢ Boils: Apply pounded leaves as poultice daily. †¢ Diuretic: Boil 2 tbsp chopped leaves in 2 glasses of water for 15 minutes. Take 1/2 of the decoction after every meal, 3 times a day. Reference: Am J Chin Med. 2008;36(2):411-24. International Journal of Applied Science and Engineering . 2005. 3, 3: 195-202 3. Biological Activities 3.1. Antitumor Activity Hasegawa et al. extracted a dihydroflavonol from B. balsamifera as a result of screening among more than 150 plant materials [12]. The dihydroflavonol components showed the most significant synergism with tumor related apoptosis inducing ligand (TRAIL). It enhanced the level of TRAIL-R2 promoter activity and promoted the expression of surface protein in a p53-independent manner. The ethanol extract of B. balsamifera leaves was tested on male mice to investigate its hepatoxicity. The results exhibited that the hepatic cells, sitplasm, nucleus, and sinusoid of the mice liver were damaged through some changes in the liver color and texture . The methanol extract of B. balsamifera inhibited the growth in rat and showed no cytotoxicity on human hepatocellular carcinoma cells. The methanol extract decreased the expression of cyclin-E and phosphorylation of retinoblastoma (Rb) protein resulting in cell cycle arrest. Likewise, it decreased the level of the proliferation related ligand (APRIL) [60,61]. Moreover, the methanol extract of B. balsamifera was used to determine its cytotoxicity on a panel of human cancer cell lines by MTT assay. There was no regular or acute cytotoxicity on the cells of HepG2, HCT-116, T-47D, NCl-H23 and CCD-18Co [62]. Saewan et al. found six compounds out of nine isolated flavonoids to have cytotoxicity against KB, MCF-7, and NCI-H187 cancer cell lines [14]. These six compounds were evaluated for cytotoxicity against KB,  MCF-7, and NCI-H187 cancer cell lines. Three compounds were active against the KB cells with the IC50 values of 17.09, 47.72, and 17.83 ÃŽ ¼g/mL, respectively. Another three compounds exhibited a moderate activity against the NCI-H187 cells with the IC50 values of 16.29, 29.97, and 20.59 ÃŽ ¼g/mL. Luteolin-7-methyl ether showed a strong cytotoxicity against human lung cancer (NCI-H187) cell lines with an IC50 of 1.29 ÃŽ ¼g/mL and a moderate toxicity against oral cavity cancer (KB) cell lines with an IC50 of 17.83 ÃŽ ¼g/mL. Li et al. studied the antitumor activity determined by means of 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay [13]. The three endophytic streptomycetes strains of B. balsamifera, including: YIM 56092, YIM 56093, and YIM 56099 exhibited anticancer activity. Yet, different strains displayed different antitumor activities. The YIM 56092 strain displayed a cytotoxic activity on polyketide synthases I (PKS-I) nonribosomal peptide synthetases (NRPS) and P388D1. The YIM 56093 strain displayed a cytotoxic activity on PKS-â… ¡, NRPS, and P388D1. The YIM 56099 was on the PKS-I, PKS-II, and NRPS. Fuijimoto et al., extracted blumealactone A, B, and C from sambong’s dried leaves and found them could inhibit the growth of Yoshida sarcoma at the concentration of 5–10 ÃŽ ¼g/ml [54]. Lee disclosed a medication combination including sambong (Ainaxiang) and found it could enhance the efficiency of curing hepatoma and pancreatic cancer treatments [63]. Molecules 201 4, 19 9462 3.5. Anti-Microbial and Anti-Inflammation Activity Ongsakul et al. claimed that the crude aqueous and ethanolic extracts of B. balsamifera displayed no significant antibacterial activity against the strains of Staphylococcus aureus and Escherichia coli [73]. However, the stain of B. balsamifera, including YIM 56092 and YIM 56093, displayed a significant activity against S. epidermidis, such that YIM 56099 was active against E. coli. There seems to be no antimicrobial activity against S. aureus, Klebsiella pneumonia, and Candida albicans [13]. Chenisolated twelve new compounds [9], four of which displayed inhibitory activities against LPS-induced NO production in RAW 264.7 with the IC50 values of 40.06, 46.35, 57.80, and 59.44 ÃŽ ¼g/mL, respectively. Sakee et al. reported the essential oil of B. balsamifera to have a minimum inhibitory concentration (MIC) of 150 ÃŽ ¼g/mL and 1.2 mg/mL against Bacillus cereus, S. aureus and Candida  albicans, respectively [74]. Furthermore, the hexane extract inhibited Enterobacter cloacae and S. aureus. These results suggested that the extracts of B. balsamifera possessed an activity against certain kinds of infectious and toxin-producing microorganisms. It could potentially be utilized to prevent and treat microbial diseases. 3.6. Antiplasmodial Activities According to the traditional efficacy of relieving fever, the methanol extract of B. balsamifera from Forest Research Institute Malaysia was investigated for any potential antiplasmodial activity. The extracts of roots and stems exhibited some activity against Plasmodium falciparum D10 strain (sensitive strain) with an IC50 value of (26.25  ± 2.47) ÃŽ ¼g/mL and (7.75  ± 0.35) ÃŽ ¼g/mL, respectively [75]. 3.8. Platelet Aggregation Activities The concentration of 1.26 ÃŽ ¼mol/L blumeatin displayed a significant promoting activity on the rat and human platelet aggregation caused by arachidonic acid, 5-hydotypamice, and epinephrine. However, concentrations of 0.315 and 2.52 ÃŽ ¼mol/L inhibited platelet aggregation. It suggested that the effects of blumeatin on the platelet aggregation were dependent upon the concentration used. The injection of B. balsamifera extracts decreased the blood pressure, expanded the blood vessels, and inhibited the sympathetic nervous system in order to address the high pressure and insomnia. The infusion of the plant also had the function of diuresis [67] Mayana (Coeus blumei Benth.) Coleus leaves are commonly known as ati-ati leaves in Malaysia. Previous study has shown that the Coleus leaves have high antioxidant activity and nutritional value. The present work is to investigate whether antioxidant, minerals and phenolic content can be extracted by boiling the leaves in water. The antioxidant was determined by mixing the extract solution with DPPH (2, 2-Diphenyl-1-Picrylhydrazyl) solution using different ratios. Acid ascorbic acid was used as standard in measurement by Uv-Vis Spectrophotometer. Phenolic content was measured by Uv-Vis Spectrophotometer using Gallic acid as standard. There is about 40.77 wt % of antioxidant  activity, 6.256998 wt% of total phenolic content, and some minerals (magnesium, calcium, iron and zinc) existing in solution after the Coleus blumei leaves were removed. The wt% of the phenolic content is directly proportional to the wt% of antioxidant activity. The mineral concentration, antioxidant activity and phenolic content seemed to be highly correlated. As a conclusion, it is proven that the Coleus blumei leaves have high potential value for the nutritional purpose. 2.1 Definition of Coleus Coleus is a name which derives from an earlier classification under the genus name Coleus, species of which are currently included in either Solenostemon or another genus, Plectranthus. The word Coleus come from the Greek â€Å"koleus’, meaning sheath. It is believed that there are 150 species of Coleus .It is a genus of perennial plants, native to tropical Africa, Asia, Australia, the East Indies, the Malay Archipelago, and the Philippines. Many cultivars of the Southeast Asian species Coleus have been selected for their colorful variegated leaves, usually with sharp contrast between the colors where the leaves are green, pink, yellow, maroon, and red. Typically, in Malaysia this plant known as ati-ati. The plants need a well condition of in moist-drained soil to grow, and typically grow 0.5-1 m tall, though some may grow as tall as 2 meters. They are heat-tolerant, though they do less well in full sun in subtropical areas than in the shade. The leaves of the green type are often eaten raw with bread and butter. The chopped leaves are also used as a substitute for sage (Salvia officinalis Linn.) in stuffing. C. aromaticus is used for seasoning meat dishes and in food products (Uphof, 1959) while a decoction of its leaves is administered in cases of chronic cough and asthma (CSIR, 1992). It is considered to be an antispasmodic, stimulant and stomachic and is used for the treatment of headache, fever, epilepsy and dyspepsia (Khory &Katrak, 1999; Morton, 1992) . 2.2 Antioxidant An antioxidant in food is really important as it can protect human body from free radicals activity. It is also has capable of slowing or preventing the oxidation of other molecules. When electrons are transferred form a substance to an oxidizing agent, it called as oxidation reaction. Free radicals can be produced during the Oxidation reactions, where the start  chain reactions that damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates, and inhibit other oxidation reactions by being oxidized themselves. As a result, antioxidants are often reducing agents such as thiols or polyphenols. Although oxidation reactions are crucial for life, they can also be damaging; hence, plants and animals maintain complex systems of multiple types of antioxidants, such as glutathione, vitamin C, and vitamin E as well as enzymes such as catalase, superoxide dismutase and various peroxidases. Low levels of antioxidants, or inhibition of the antioxidant enzym es, causes oxidative stress and may damage or kill cells. As oxidative stress might be an important part of many human diseases, the use of antioxidants in pharmacology is intensively studied, particularly as treatments for stroke and neurodegenerative diseases. However, it is unknown whether oxidative stress is the cause or the consequence of disease. Antioxidants are also widely used as ingredients in dietary supplements in the hope of maintaining health and preventing diseases such as cancer and coronary heart disease. Although some studies have suggested antioxidant supplements have health benefits, other large clinical trials did not detect any benefit for the formulations tested, and excess supplementation may be harmful In addition to these uses in medicine, antioxidants have many industrial uses, such as preservatives in food and cosmetics and preventing the degradation of rubber and gasoline. Current research into free radicals has confirmed that foods rich in antioxidants play an essential role in the prevention of cardiovascular diseases and cancers. As far as our literature survey could ascertain, antioxidant activities of this plant have not previously been published. Hence, the previous work investigated the possible antioxidat ive effects of freeze-dried powder obtained from aqueous extract of fresh leaves of C. aromaticus. In this study, they had examined the antioxidant activity of CAE (C.aromaticus hydroalcoholic extract) employing various in vitro assay systems, such as the ÃŽ ²- carotene-linoleate model system, DPPH (2,2-Diphenyl-1-Picrylhydrazyl)/superoxide/ nitric oxide radical scavenging, reducing power and iron ion chelation, in order to understand the usefulness of this plant as a foodstuff as well as in medicine. 2.2.1 Antioxidant Assay using a ÃŽ ²-carotene-linoleate Model System On the previous experiment, the antioxidant activity of the extract was measured by the bleaching of  ÃŽ ²-carotene. By adding CAE and BHT (Butylated Hydroxytoluene) at various concentrations, it can prevent the bleaching of ÃŽ ²-carotene to different degrees. ÃŽ ²-Carotene in this model system undergoes rapid discoloration in the absence of an antioxidant. This is because of the coupled oxidation of ÃŽ ²-carotene and linoleic acid, which generates free radicals. The linoleic acid free radical, formed upon the abstraction of a hydrogen atom from one of its diallylic methylene groups, which attacks the highly unsaturated ÃŽ ²-carotene molecules. As a result, ÃŽ ²-carotene will be oxidized and broken down in part; subsequently, the system looses its chromophore and characteristic orange colour, which can be monitored spectrophotometrically. The presence of different antioxidants can hinder the extent of ÃŽ ²-carotene bleaching by neutralizing the linoleate free radical and other free radicals formed in the system (Jayaprakasha, Singh, & Sakariah, 2001). It also showed that the CAE was found to hinder the extent of ÃŽ ²-carotene bleaching by neutralizing the linoleate-free radical and other free radicals formed in the system. In comparison, the CAE showed an appreciable antioxidant activity of 83.0% at 250 ÃŽ ¼g/ml, while BHT, a synthetic antioxidant had 89.6% antioxidant activity at 100 ÃŽ ¼g/ml. Table 2.1: Antioxidant activity of aqueous extract of C. aromaticus in ÃŽ ²-carotenelinoleate System Sample Concentration (ÃŽ ¼g/ml) Antioxidant activity (%) Aqueous extract 125 53.2  ± 1.04 250 83.0  ± 1.33 500 91.3  ± 1.41 BHT 50 64.2  ± 1.81 100 89.6  ± 1.52 200 95.3  ± 1.33 2.2.2 DPPH Radical-scavenging Activity The CAE showed a concentration-dependent antiradical activity by inhibiting DPPH radical with an EC50 value of 210 ÃŽ ¼g/ml (Table 2). DPPH is usually used as a substrate to evaluate antioxidative activity of antioxidants (Oyaizu, 1986). The method is based on the reduction of methanolic DPPH solution in the presence of a hydrogen donating antioxidant, due to the formation of the non-radical form DPPH-H by the reaction. The extract was able to reduce the stable radical DPPH to the yellow-coloured diphenylpicrylhydrazine. It has  been found that cysteine, glutathione, ascorbic acid, tocopherol, polyhydroxy aromatic compounds (e.g., hydroquinone, pyrogallol, gallic acid), and aromatic amines (e.g., p-phenylene diamine, p aminophenol), reduce and decolorise 1,1-diphenyl-2-picrylhydrazyl by their hydrogen donating ability (Blois,  Oregano (Origanum vulgare L.)  oregano (É™rÄ•gˈənÃ… ) [key], name for several herbs used for flavoring food. A plant of the family Labiatae (mint family),Origanum vulgare, also called Spanish thyme and wild marjoram, is the usual source for the spice sold as oregano in the Mediterranean countries and in the United States. Its flavor is similar to that of marjoram but slightly less sweet. In Spain and Italy many other Origanum species are also grown as oregano. A related herb ( Coleus amboinicius ) of the same family, called suganda in its native Indomalaysia, is known as oregano in the Philippines and Mexico, where it is a popular flavoring. Several other herbs also provide spices called oregano, e.g., species ofLippia and Lantana of the verbena family. In all cases the flavoring is made from the dried herbage. Oregano is classified in the division Magnoliophyta, class Magnoliopsida, order Lamiales, family Labiatae . All rights reserved. genus Origanum is a member of the Lamiaceae family and has a complex taxonomy [1]. O. vulgare plays a primary role among culinary herbs in world trade [2]. It is distributed all over Europe, West and Central Asia up to Taiwan [3]. The use of O. vulgare as medicinal plant is believed to be due to biological properties of p-cymene and carvacrol. Bernà ¡th [4] has noted that there are intras- pecific taxa of oregano having no â€Å"oregano† character that is based on the presence of carvacrol. Oregano is the common name for a general aroma and flavour primarily derived from more than 60 plant species used all over the world as a spice [5]. Four main groups of plants com- monly used for culinary purposes can be distinguished, i.e., Greek oregano (Origanum vulgare ssp. hirtum (Link) Ietswaart); Spanish origano (Coridohymus capitatus (L.) [2]; Turkish oregano (Origanum onites L.); and Mexican oregano (Lippia graveolens HBK [6]. Origano is the commercial name of those Origanum species that are rich in the phenolic  monoterpenoids, mainly carvacrol and occasionally thymol [7]. A number of chemically related compounds i.e. p-cymene; ÃŽ ³-terpinene, carvacrol methyl ethers, thymol methyl ethers, carvacrol acetates and thymol acetates; as well as p-cymenene, p-cy- men-8-ol, p-cymen-7-ol, thymoquinone, and thymohy- droquinone are present in the oil of Origanum vulgare which is extremely rich in essential oils (up to 7%) with carvacrol as a major constituent present in very high quantity (75% – 95%), followed by p-cymene (4% – 14%) and ÃŽ ³-terpinene (1% – 10%). It seems possible that the uses of the plant in traditional medicine can be attributed to the known biological properties of p-cymene and car- vacrol [8]. Many of the studies confirmed the medicinal effects of oregano for human health. The Origanum spe- cies, which are rich in essential oils, have been used for thousands of years as spices and as local medicines in traditional medicine [9]. About 20 European public in- stitutions hold genetic resources of different species of oregano [10]. Marjoram (Origanum vulgare L.) is one of medicinal aromatic plants found wholesale almost in all areas of Albania, which is a perennial plant usually grows in dry area in smaller groups. Oregano plants are collect- ed from natural habitats and used as raw materials in the pharmaceutical, cosmetic and food industry [11]. But many countries start to cultivate it in different areas. In botanical aspects, the oregano populations differ from one to another, that is they vary depending on the content and composition of essential oils [12]. From the quantity and quality of essential oils the values of this plant were determined [11,12]. The different results showed that the effects of oregano antioxidante are associated with high content of essential oils, thymol and carvacrols, and these are the main ingredients in oregano oil. The con- tents of Thymol and Carvacrol in oregano give it differ- ent properties [13]. According to the studies, carvacrol is a powerful bactericidal agent, and provides protection against mold and other common bacteria. The main ob- jective in our study was to investigate the different re- gions and to find the variation for oil content in oregano plant populations. The research expedition was organized in 2012 in the whole territory of Albania. During this expedition are identified and collected 62 accessions. At each location were taken of the 50 samples which derived a main rep- resentativ sample. From the total samples collected, were selected 16 samples mostly widespread of natural popu- lations of  origano (Origanum vulgare L. sp. vulgare and sp. hirtum). Those samples you perform analyzes for content of oils and their components. The confirmation of 53 essential oil was made to analyses: ÃŽ ²-Pinene, p- Cymene, ÃŽ ³-Terpinene, Linalool, Terpinene-4-ol, Thymol, Carvacrol dhe Caryophyllene oxide. The overground parts of the flowering plants (20 – 25 cm from the top) were collected during the summer of 2012. The plant material was air dried, packed in paper bags and kept in a dark and cool place until analysis. Plant identity was verified and voucher specimens were deposited at the Institute of Pharmacognosy, Faculty of Pharmacy, Skopje. 2.2. Essential Oil Isolation Essential oil isolation from oregano was performed by hydro distillation in all-glass Clevenger apparatus fol- lowing this procedure: 20 g of the plant material was stored in 500 mL flask where 250 mL of water R was used as distillation liquid and 0.5 mL of xylene R was added in the graduate tube. The Distillation was per- formed for 2.5 h with a rate of 2 – 3 mL/min. GC and GC-MS analyses: Agilent 7890Ð  Gas Chro- matography system equipped with flame ionization de- tector (FID) and Agilent 5975C Mass Quadrupole detec- tor as well as capillary flow technology which enable simultaneous analysis of the sample on both detectors. HP-5 ms (30 m Ãâ€" 0.25 mm, film thickness 0.25 ï  ­m) cap- illary column was used. Operating conditions were as follows: GC Method for essential oils: oven temperature 60 °C (0 min), 3 °C/min to 240 °C (held for 1 min) and 10 °C/min to 280 °C (held for 1 min); helium as carrier gas at a flow rate of 1 mL/min; injector T = 220 °C and FID T = 270 °C. 1 ï  ­L of injection volume was injected at split ratio 1:1. The mass spectrometry conditions were: ionization voltage 70 eV, ion source temperature 230 °C, transfer line temperature 280 °C and mass range from 50 – 500 Da. The MS was operated in scan mode. GC Method for Head Space: oven temperature 60 °C, 20 °C/min to 280 °C; helium as carrier gas at a flow rate of 1 mL/min; injector T = 260 °C and FID T = 270 °C. 1000 ï  ­L of injec- tion volume was injected at split ratio 1:1. The mass spectrometry conditions were: ionization voltage 70 eV, ion source temperature 230 °C, transfer line temperature 280 °C and mass range from 50 – 500 Da. The MS was operated in scan mode. Head Space method: Incubation Temperature 80 °C, Incubation Time 5.00 m:ss, Syringe Temperature 85 °C, Agitator Speed 500 rpm, Fill Speed 500 ÃŽ ¼l/s, Pullup Delay 500 ms, Inject to GC, Injection speed 500 ÃŽ ¼l/s, Pre  Inject Delay 500 ms, Post Inject De- lay 500 ms, Flush Time (m:ss) 0:10, GC Run time (m:ss) 10:00. Identification of the components: Identification of the components was made by comparing mass spectra of components in essential oils with those from Nist, Wiley and Adams mass spectra libraries, by AMDIS (Auto- mated Mass Spectral Deconvolution and Identification System) and by comparing literature and estimated Ko-vat’s (retention) indices that were determined using mix-ture of homologous series of normal alkanes from C9 to C25 in hexane, under the same above mentioned condi- tions. The percentage ratio of the components was com- puted by the normalization method of the GC/FID peak areas and average values were taken into further consid- eration (n = 3). 2.3. Statistical Analyses All statistical analyses were performed with the SPSS software (version 15.0, SPSS) [14]. Means values and variation coefficients were used in the statistical analyses. Effects of the studied traits were evaluated by ANOVA. In order to assess the differentiation of plants of oregano based on all variables that were measured, the Canonical Discriminate Analyses (CDA) was applied Psidium guajava (Guava): Chronic degenerative diseases have reached epidemic proportions in industrialized and developing countries. Many studies have shown that plant can be helpful to prevent or treat diseases. Psidium guajava is a small medicinal tree that is native to South America and Brazil is among the world’s top producers and most of the country’s production is destined for the food industry. It is popularly known as guava and has been used traditionally as a medicinal plant throughout the world for a number of ailments. The aim of this review is to present some chemical compounds in P. guajava and their pharmacological effects. The main constituents of guava leaves are phenolic compounds, isoflavonoids, gallic acid, catechin, epicathechin, rutin, naringenin, kaempferol. The pulp is rich in ascorbic acid, carotenoids (lycopene, ÃŽ ²-carotene and ÃŽ ²-cryptoxanthin). The seeds,  skin and barks possess glycosids, carotenoids and phenolic compounds. All parts of the plant have been used for different purposes: hepatoprotection, antioxidant, anti-inflammatory, antispasmodic, anti-cancer, antimicrobial, anti-hyperglycemic, analgesic, endothelial progenitor cells, anti-stomachache and anti-diarrhea. P. guajava has many effects on health and that it should be researched more extensively in clinical trials. Furthermore leaves, seeds and peel are treated as wastes by the food processing industry and are discarded, so their use may reduce the disposal of these parts of guava as pollutants. Psidium guajava; Anti-inflammatory; Antioxidant; Cancer; Diabetes; Dyslipidemia Industrialization has led to many modifications in the lifestyle of the world’s populations, giving rise to increase the indices of several diseases, including chronic degenerative diseases such as insulin resistance, diabetes mellitus, dyslipidemia, metabolic syndrome and cardiovascular diseases, reducing the quality of life and increasing costs on hospitalizations, medications and other public health interventions. Studies have demonstrated that the consumption of fruits, vegetables and seeds can be helpful to prevent the risk factors of many diseases due to the bioactive compounds. Many plants have been used for the purpose of reducing risk factors associated with the occurrence of chronic disorders and for many other purposes Psidium guajava L. is a small medicinal tree that is native to South America. It is popularly known as guava (family Myrtaceae) and has been used traditionally as a medicinal plant throughout the world for a number of ailments. There are two most common varieties of guava: the red (P. guajava var. pomifera) and the white (P. guajava var. pyrifera) All parts of this tree, including fruits, leaves, bark, and roots, have been  used for treating stomachache and diarrhea in many countries. Leaves, pulp and seeds are used to treat respiratory and gastrointestinal disorders, and as an antispasmodic, anti-inflammatory, as a cough sedative, anti-diarrheic, in the management of hypertension, obesity and in the control of diabetes mellitus. It also possesses anticancer properties . The seeds are used as antimicrobial, gastrointestinal, anti-allergic and anticarcinogenic activity. Brazil is among the world’s top producers of guava and most of the country’s production is destined for the food industry to produce candies, juices, jams and frozen pulp. As result of the fruit process there is a discard of the leaves, seeds, part of the peel and pulp fraction not separated in the physical depulping process. The high cost of pharmaceutical medications conduces to the search for alternative medicines to treat many ailments. In view of this, studies are necessary to confirm the effects of medicinal plants. The aim of this review is to show that several studies have demonstrated the presence of many different chemical compounds in P. guajava and their pharmacological effects. Medical Properties and Composition of Guava Pulp The main constituents of guava are vitamins, tanins, phenolic compounds, flavonoids, essential oils, sesquiterpene alcohols and triterpenoid acids. These and other compounds are related to many health effects of guava . Some authors have found high concentrations of carotenoids (beta-carotene, lycopene, and beta-cryptoxanthin), vitamin C and polyphenols in guava pulp. Lycopene has been correlated with the prevention of cardiovascular damage because of its positive effects on dyslipidemia . Ascorbic acid is recognized for its important antioxidant effects . Shu et al. isolated nine triterpenoids from guava fruit: ursolic acid; 1beta, 3beta-dihydroxyurs-12-en-28-oic acid; 2alpha,3beta-dihydroxyurs-  12-en-28-oic acid; 3beta,19alpha-dihydroxyurs-12en-28-oic acid; 19a-hydroxylurs-12-en-28-oic acid-3-O-alpha-L-arabinopyrano- side; 3beta, 23-dihydroxy urs-12-en-28-oic acid; 3beta, 19alpha, 23beta- tri-hydroxylurs-12-en-28-oic acid; 2alpha, 3beta,19alpha, 23beta-tetrahydroxyurs-12-en-28-oic acid and 3alpha,19alpha,23,24-tetrahydroxyurs -12-en-28-oic acid. Ursolic acid and other triterpenoids are associated with anti-cancer properties. Shu et al. found three benzophenone glycosides in ripe edible fruits of P. guajava L: 2, 6-dihydroxy-3, 5-dimethyl-4-O-beta-D-glucopyranosyl-benzophenone; 2, 6-dihydroxy-3-methyl-4-O-(6’’-O-galloyl-beta-D-glucopyranosyl)-benzophenone and 2, 6-dihydroxy-3, 5-dimethyl-4-O-(6’’-O-galloyl-beta-D-glucopyranosyl)-benzophenone. Benzophenone glycosides have inhibitory effect on triglycerides accumulation. Thuaytong and Anprung found antioxidant activity in guava and the major constituents identified in white and red guavas were ascorbic acid, gallic acid, catechin equivalents, cinnamyl alcohol, ethyl benzoate, ß-caryophyllene, (E)-3-hexenyl acetate and ÃŽ ±-bisabolene. The antioxidant properties of the guava pulp can be related to anti-cancer effects. Studies with humans have found that the consumption of guava for a period of 12 weeks reduced blood pressure by 8%, total cholesterol levels by 9%, triacylglycerides by almost 8%, and induced an 8% increase in the levels of HDL-c. Farinazzi et al.showed that animals treated with guava pulp juice had significantly lower body weight, glycemia, cholesterol and triglycerides levels and significantly augmented the levels of HDL-c when compared to the animals from the control group. Lyophilized pulp of P. guajava in diabetic rats induces to significant hypoglycemic effects probably due to its antioxidant activity of compounds present in the pulp. Medical Properties and Composition of Guava Leaves Guava leaf extract has analgesic, anti-inflammatory, antimicrobial, hepatoprotective and antioxidant activities. These effects are probably due to the presence of phenolic compounds.   Jimà ©nez-Escrig et al., Wang et al. and Haida et. reported the presence of higher amounts of phenolic compounds with antioxidant activity in the leaves of white (Psidium guajava var. pyrifera L.) and red guava (Psidium guajava var. pomifera L.) when compared with other vegetable species. Wu et al, Melo et al. and Chen et al found gallic acid, catechins, epicatechins, rutin, naringenin and kaempferol in the leaves. Studies have shown that gallic acid, catechin, and epicatechin inhibit pancreatic cholesterol esterase, which decreases cholesterol levels. Catechins are important as a preventive treatment for diabetes type 2 and obesity. Quercetin has been associated to decreased mortality from heart disease and decreased incidence of stroke. Quercetin presents hypocholesterolemic and antioxidant activity. Rutin is effective in the inhibition of triglyceride accumulation in adipocytes. Naringenin and kaempferol can promote moderate cytostatic activity against all cell lines and kaempferol can be useful as anticancer . Fu et al.elucidated the structure of three novel sesquiterpenoid- based meroterpenoids of psidials A-C found in guava leaves. Matsuzak et al.isolated two new benzophenone galloyl glycosides, guavinosides A and B, and a quercetin galloyl glycoside, guavinoside C as well as five known quercetin glycosides from guava leaves. The structures of the novel glycosides were elucidated to be 2,4,6-trihydroxybenzophenone 4-O-(6’’-O-galloyl)-beta-D: -glucopyranoside (1, guavinoside A); 2,4,6-trihydroxy-3,5-dimethylbenzophenone 4-O-(6’’-O-galloyl)-beta-D: -glucopyranoside (2, guavinoside B), and quercetin 3-O-(5’’-O-galloyl)-alpha-L: -arabinofuranoside (3, guavinoside C). Kim et al.related that the guava leaves contain ascorbic acid, citric acid,  acetic acid, epicatechin, xanthine, protocatechuic acid, glutamic acid, asparagine, malonic acid, trans-aconitic acid, maleic acid and cis-aconitic acid. Ghosh et al.isolated two terpenoids from the leaf extract of P. guajava (betulinic acid and lupeol) and reported their potential antimicrobial and phytotoxic activities. Betulinic acid and lupeol can be used in the treatment of diabetes, cardiovascular desease, obesity and atherosclerosis. Shao et al. isolated two terpenoids from guava leaves: Psiguadials A and B, two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A and guajadial. Shu et al.identified one diphenylmethane, one benzophenone, and eight flavonoids from guava fresh leaves(2,6-dihydroxy-3-formaldehyde-5-methyl-4-O-(6†³-O-galloyl-ÃŽ ²-D-glucopyranosyl)-diphenylmethane; 2,6-dihydroxy-3,5-dimethyl-4-O-(6†³-O-galloyl-ÃŽ ²-D-glucopyranosyl)-benzophenone; kaempferol; quercetin; quercitrin; isoquercitrin; guaijaverin; avicularin; hyperoside and reynoutrin. Guaijaverin has high potential antiplaque agent by inhibiting the growth of the Streptococcus mutans. Avicularin and guaijaverin work as urease inhibitors (against Helicobacter pylori urease). Shao et al. isolated four new triterpenoids, psiguanins A-D (1-4), and with 13 known compounds from the leaves of guava.   Guava aqueous leaf extract showed anti-trypanosomal properties in rats experimentally infected with Trypanosoma brucei brucei.   Rahim et al.evaluated the effects of aqueous mixture and water soluble methanol extract from guava leaves and bark against multi-drug-resistant Vibrio cholera and found strong antibacterial activity. They concluded that this plant offers potential for controlling epidemics of cholera. Birdi et al. and Birdi et al. related that P. guajava leaves have a broad spectrum of antimicrobial action (as antigiardial and antirotaviral activity) that could be effective in controlling diarrhea due to a wide range of pathogens. The antimicrobial activity can be linked to the presence of flavonoids  extracted from guava leaves. Deguchi and Miyazaki reported that guava leaves infusion not only reduced postprandial glycemia and improved hyperinsulinemia in murine models but also contributed to reduce hypercholesterolemia, hypertriglyceridemia and hypoadiponectinemia in the animals of their study. Rutin and kaempferol found in guava leaves are compounds related to the decrease of HMG-CoA reductase activity in hepatic tissue and improve lipid profiles. Akinmoladun et al. studied methanol extracts of some fruits, including P. guajava, and demonstrated that there is a good correlation between total phenolic contents and reductive potential and a fair correlation between total phenolic contents and lipid peroxidation inhibitory activity. Several studies have shown that aqueous extract of Psidium guajava contains components with LDL-c antiglycation activity, suggesting its contribution to the prevention of neurodegenerative and cardiovascular diseases Other studies have found cardioprotective effects of aqueous extract of P. guajava in myocardial ischemia-reperfusion injury in isolated rat hearts, primarily through their radical-scavenging actions. Ojewole identified the presence of phenolic compounds in the leaves demonstrating their hypoglycemic and hypotensive effects on diabetic rats treated with aqueous leaf extract. Soman et al. reported a decline in the levels of glycated hemoglobin and fructosamines, as well as a significant reduction in the glycemic levels of diabetic rats treated with guava leaf extract. Singh and Marar studied the effects of Psidium guajava leaves on the inhibition of the activity intestinal glycosidases related with postprandial hyperglycemia, suggesting its use for the treatment of individuals with type 2 diabetes.Other studies have demonstrated that guava leaf and peel extracts also had hypoglycemic effects on experimental models drug-induced to severe conditions of diabetes. Wu et al.found that the phenolic compounds, gallic acid, catechins and  quercetins in guava leaves inhibited the glycation of proteins suggesting its use for the prevention of diabetes complications.The Psiguadials A, B and guajadial isolated by Shao et al. exhibited potent inhibitory effects on the growth of human hepatoma cells. Kim et al. related that the guava leaves contain compounds that promote free radical scavenging activity showing promising antioxidant properties. Dutta and Das identified significant anti-inflammatory activity of the ethanol extract of guava leaves in experimental models, while Kawakami et al. observed the antiproliferative activity of the leaves through inhibition of the catalytic activity of prostaglandin endoperoxide H synthases involved in the inflammatory process. Guava budding leaves aqueous extract possesses an extremely high content of poly phenolic and isoflavonoids and suppresses the cell migration and the angiogenesis. In view of this, clinically it has the potential to be used as an adjuvant anti-cancer chemo preventive . Matsuzak et al. isolated phenolic glycosides from guava leaves and showed significant inhibitory activity against histamine release from rat peritoneal mast cells, and nitric oxide production from a murine macrophage-like cell line. Roy and Das studied the hepatoprotective activity of different extracts of P. guajava (petroleum ether, chloroform, ethyl acetate, methanol and aqueous) in acute experimental liver injury induced by carbon tetrachloride and paracetamol. The effects were compared with a known hepatoprotective agent and observed that the best effects came from guava methanolic leaf extract that significantly reduced the elevated serum levels of enzymes (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase) and bilirubin. P. guajava leaves exhibit high capacity to reduced polymerization and aggregation of sickle cell hemoglobin molecule. This molecule is a product of a defective genetic code of hemoglobin molecule and is prone to deoxygenation-induced polymerization and has low insolubility. The development of chemical modification agents that reduce the tendency of sickle cell hemoglobin molecule to aggregate represents an important  chemotherapeutic goal. Guava extract leaves can be responsible for membrane stabilizing effect on sickle erythrocytes that are susceptible to endogenous free radical-mediated oxidative damage. This effect can be attributed to the flavonoids, triterpenoids and host of other secondary plant metabolites . Chen et al. found that aqueous extract of guava budding leaves possess anti-prostate cancer activity in a cell line model and concluded they are promising anti-androgen-sensitive prostate cancer agent. Han et al. studied the effects of P. guajava ethyl acetate extract on atopic dermatitis and found that it inhibits chemokine expression in keratinocytes what suggests this extract can have possible therapeutic application in atopic dermatitis and other inflammatory skin diseases. Methanol extracts of the leaves can also be useful in the treatment of gastric ulcer disorders possibly due to the presence of volatile oil, flavonoids and saponins Methanolic extract of guava leaves can exhibit wound healing effects and this property can be explained by the presence of tannins and flavonoids. Guava leaves extract also can show anti cough effects as shown by Jaiarj et al. Medical Properties and Composition of Guava Discarded Products As told before, the fruit process results in the discard of the leaves, seeds, part of the peel and pulp. Some studies showed the presence of total phenolic compounds in the agroindustrial wastes (seeds, skin and pulp) of guava, confirming its antioxidant activity . Leaves, seeds and peels of fruits have significant proportions of bioactive compounds with beneficial physiological and metabolic properties. Its antioxidants can control body weight and biochemical variables like glycemia, dyslipidemia, hypertension and other risks of cardiovascular diseases. The antioxidant properties of the guava seeds extracts can be associated to anti-cancer effects on both hematological and solid neoplasms  and the antioxidant properties of the guava peel can be related to anti-cancer effects. Castro-Vargas et al.and Ojewole extracted and identified significant levels of carotenoids and total phenolic compounds from guava seeds. Seeds exhibit antimicrobial, gastrointestinal and anticarcinogenic activities probably due to the presence of phenolic glycosides in the composition. Farinazzi et al. showed that Wistar rats treated with guava seed had significantly lower glycemia, cholesterol and triglycerides levels and body weight. These animals significantly increased HDL-c levels. Rai et al. reported hypolipidemic and hepatoprotective effects in diabetic rats treated with aqueous extract of lyophilized guava peel.   Psidium guajava stem-bark extract can be used to treat malaria because it presents antiplasmodial activities possibly due to the presence of anthraquinones, flavonoids, seccoirridoids and terpenoids. Related study Many researchers have been demonstrating the presence of a wide variety of bioactive compounds in the leaf, seed and bark of Psidium guajava that are capable of showing beneficial effects on human health. If we consider that chronic degenerative diseases have reached epidemic proportions in many countries and increase the socio-economic burden for the public health system, it is necessary to find non-allopathic alternatives that minimize risk factors of these diseases and help in the treatment. Furthermore, population consumes medicinal plants also to treat other kind or diseases because of high costs of allopathic medications. The studies using P. guajava bring information that may provide validation for its medicinal uses but it should be researched more extensively in clinical trials so it could be used for prevention and as an adjuvant in the treatment of numerous disorders. Nevertheless we should emphasize the importance of experimental and clinical  studies involving more specific factors related to the bioavailability of the compounds, as well as the effective and safe doses to be used by individuals for the prevention and treatment of various disorders. Katakataka( bryopphyllum pinnatum) Constituents †¢ Phytochemical screenings have yielded alkaloids, triterpenes, glycosides, flavonoids, steroids, butadienolides, lipids, and organic acids. †¢ Yields arachidic acid, astragalin, behenic acid, beta amyrin, benzenoids, bersaldegenin, beta-sitosterol, bryophollenone, bryophollone, bryophyllin,caffeic acid, ferulic acid, quercetin, steroids, and taraxerol. †¢ Phytochemical evaluation of leaf extract yielded bryophyllum A, B and C, a potent cytotoxic bufadienolide orthoacetate. †¢ Bufadienolide has been reported to be poisonous with digitalis-toxicity type cardiac effects (slowing of heart rate, heart blocks and potentially fatal ventricular arrhythmias. †¢ Bryophillin A, a bufadienolide compound, has shown anti-tumor promoting activity. †¢ Leaves yield malic acid. Fractionation of an EtOAc extract yielded seven kaempferol rhamnosides: kaempferol 3-O-ÃŽ ±-L-(2-acetyl)rhamnopyranoside-7-O-ÃŽ ±-L-rhamnopyranoside, kaempferol 3-O-ÃŽ ±-L-(3-acetyl)rhamnopyranoside-7-O-ÃŽ ±-L-rhamnopyranoside, kaempferol 3-O-ÃŽ ±-L-(4-acetyl)rhamnopyranoside-7-O-ÃŽ ±-L-rhamnopyranoside, kaempferol 3-O-ÃŽ ±-D- glucopyranoside-7-O-ÃŽ ±-L-rhamnopyranoside, afzelin, and ÃŽ ±-rhamnoisorobin. (19) Properties †¢ Leaves considered astringent, antiseptic, hemostatic, refrigerant, emollient, counterirritant, mucilaginous, vulnerary, depurative, anti-inflammatory, disinfectant, and tonic. †¢ Pharmacologic studies have showed pharmacologic properties: immunomodulatory, CNS depressant, analgesic, anti-inflammatory, anti-allergic, antianaphylactic, antileishmanial, antitumorous, antiulcer, antibacterial, antifungal, antiviral, febrifuge, gastroprotective, immunosuppressive, insecticidal, sedative, muscle relaxant. Folkloric – Leaves used as astringent, antiseptic, and counterirritant against  poisonous insect bites. – Pounded fresh material is applied as a poultice for a variety of conditions: Sprains, eczema, infections, burns, carbuncle and erysipelas. – Leaves, made pliable by hold over fire, are applied to wounds, bruises, boils; also, used as poultice or power in bad ulcers. – Juice is mixed with lard and used for diarrhea, dysentery, cholera, and phthisis. – Pounded leaves are applied as poultices to the soles of the feet to stop hemorrhages. – Leaves are used as topicals in dislocation, ecchymoses, callosities. – Leaves, pounded and mixed with salt, used as plaster and applied to stomach to relieve enuresis – For boils, the whole leaf is pressed by hand, to and fro, until it becomes moist with the leaf extract. A small opening is made in the middle of the leaf which is then placed on the boil with hole over the pointing of the abscess. – For asthma, leaves of leaves places in hot water for 15 minutes, then juice squeezed out of the leaves, and drunk. – Juice of leaves used in bilious diarrhea and lithiasis. – In Ayurveda, useful in vitiated conditions of vata and pitta, cuts, wounds, hemorrhoids, menorrhagia, boils, sloughing ulcers, burns and scalds, diarrhea, dysentery, headaches, vomiting, bronchitis. – In Puerto Rico, leaf juice used as diuretic. – Leaves are rubbed or tied on the head for headaches. – Leaf decoction usually taken to lower blood pressure. – Leaf juice used for earache and ophthalmia. – In Sierre Leon, cough medicine is made from the roots. – In Brazil leaves, heated over fire and mixed with oil, are used as emollient and refrigerant for facial swelling associated with neuralgia or tooth trouble. Also, used for asthma and bronchitis. – In Jamaica, leaves used for coughs and colds. Sometimes, it is mixed with salt or honey, for headaches, colds, bronchial affections, and hypertension. Heated leaves used for swellings and abscesses. – In Africa, used for earaches, eye problems, and as diuretic. – In China used for rheumatoid arthritis, bruises, burns and ulcers. – In Nigeria, plant is considered sedative, wound-healing, diuretic, anti-inflammatory, and cough suppressant. Leaf juice used to treat boils and skin ulcers. Plant used for intestinal parasites, bronchitis,  pneumonia. Banana (Musa sapientum Linn.) The banana plant is the largest herbaceous flowering plant. The main or upright stem is actually a pseudostem, growing from a corm, to a height of 6 to 7.6 meters. Leaves are spirally arranged, as long as 2.7 meters and 60 cm wide, fragile and easily torn by wind, with the familiar frond look. Each pseudostem produces a single bunch of bananas; the pseudostem dies after fruiting, as offshoots usually develop from the base of the plant. Each pseudostem produces a single inflorescence, the banana heart, containing many bracts between rows of flowers. The banana fruits develop from the heart, in a hanging cluster made up of tiers (hands), up to 20 fruit to a tier. Distribution Cultivated throughout the Philippines in many varieties. Constituents †¢ Juice of the flower-stem contains potash, soda, lime, magnesia, alumina, chlorine, sulfuric anhydride, silica and carbon anhydride. †¢ High potassium content – a medium banana contains about 450 mg of potassium. (Because of potassium homeostasis in the body, 40K ingested is balanced by 40K potassium excreted. The net dose of a banana is zero.) †¢ Preliminary phytochemical screening of fresh steam juice yielded vitamin B, oxalic acid, sulphate, vitamin C, starch, tannin, glycosides, phenolic compounds, gum mucilage. †¢ Study yielded 6 triterpenes: 6 triterpenes: cyclomusalenol, cyclomusalenone, 24-methylenecycloartanol, stigmast-7-methylenecycloartanol, stigmast-7-en-3-ol, lanosterol, and a-amyrin and eight flavonoids. – Mineral content and nutritional value of varieties (lakatan, latundan, saba, and bungalan) Properties †¢ Demulcent, nutrient, cooling, astringent, antiscorbutic, antifebrile, restorative, emmenagogue, cardialgic, styptic. †¢ The ripe fruit is laxative, demiulcent, and nutrient. †¢ Unripe fruit is cooling and astringent. †¢ Dried fruit considered antiscorbutic. †¢ Root is antibilious and alterative. †¢ Juice of the plant is styptic. †¢ Because of its high potassium content, bananas are naturally slightly radioactive, more than other fruits. †¢ Good sources of vitamin A, fair sources of vitamin B, and good sources of vitamin C. All are deficient in calcium and phosphorus, and only fair in iron. †¢ Studies have attributed biologic activities: antiulcerogenic, antidiabetic, antiatherogenic, antidiarrheic, antitumoral, antimutagenic, antihypertensive. Parts used Leaves, fruit. Uses Edibility / Nutritional – The â€Å"puso† (male inflorescence) of saba is extensively used as a vegetable. – Unripe fruit is sugared and candied. – Ripe fruits also used in making brandy, rum, and wine. – Rich in vitamins A, B, and C; a fair source of iron. Folkloric †¢ Young leaves used for cool dressing of inflamed and blistered surfaces and as cool application for headaches. †¢ Powdered roots used for anemia and cachexia. †¢ Mucilage prepared from seeds used for catarrhal and mild inflammatory forms of diarrhea. †¢ Juice of tender roots used as mucilage for checking hemorrhages from the genitalia and air passages. †¢ In China, juice of roots used as antifebrile and restorative. †¢ Juice of the trunk applied to scalp to increase hair growth and prevent hair from falling. †¢ In West Africa, used for diarrhea. †¢ In Gambia, sap of inflorescence used for earaches. †¢ In French Guiana, flowers used as emmenagogue. †¢ In the Gold Coast, sap from roots given as enema for diarrhea. †¢ In Cambodia, Java and Malaya, juice from trunk used for dysentery and diarrhea. †¢ Juice from flowers, mixed with curds, for dysmenorrhea and menorrhagia. †¢ Flour made of green bananas used for dyspepsia with flatulence and acidity. †¢ Ripe fruit, mixed with half its weight in tamarinds and a little salt, is a valuable food in chronic dysentery and diarrhea, †¢ Cooked flower used for diabetes. Flowers also used as cardialgic. †¢ Sap of the flower used for  earaches. †¢ In Western Ghat in India, leaves are used for bandaging cuts, blisters and ulcers. †¢ Ripe bananas combined with tamarind and common salt used for dysentery. †¢ In traditional medicine in India, used for diabetes. †¢ In South-Western Nigeria, green fruits used for diabetes. Others †¢ Papermaking / Clothing: Plant fibers used in the manufacture of paper and clothes. A related species, Musa textilis (Abaca, Manila hemp) is produced on a commercial scale for its fiber use in the manufacture of paper. †¢ Wrapping / Cooking: Leaves used for wrapping food for cooking. Leaves used for polishing floors, lining pots for cooking rice. Studies †¢ Hypoglycemic / Flowers: Study on the chloroform extract of M sapientum flowers showed hypoglycemic activity with significant reduction of blood glucose, glycosylated hemoglobin and improvement in glucose tolerance. †¢ Hypoglycemic/ Fruits: Study on the green fruits of M paradisiaca indicate it possesses hypoglycemic activity and lends credence to its Nigerian folkloric use for diabetes. †¢ Antioxidant: (1) Musa sapientum flower extract showed improved antioxidant activity in diabetics. (2) A study of extracts of M. sapientum var. sylvesteris showed concentration-dependent scavenging effects, with antioxidant activity stronger than that of vitamin C. †¢ Gastroprotective: Study on the unripe plantain extract of M sapientum and unripe pawpaw meal showed alteration of the gastric phospholipid profile and through a prostaglandin pathway may have a profound effect on the gastroduodenal mucosa and implications for gastric and duodenal ulcers in rabbits. †¢ Flowers / Antihyperglycemic / Antioxidant: Study showed banana flower extract to have an antihyperglycemic action and antioxidant properties, comparatively more effective than glibenclamide. †¢ Analgesic: Study of the aqueous and ethanolic extract of Musa sapientum showed central analgesic action. †¢ Wound healing: Study of aqueous and methanolic extracts of Musa sapientum showed wound healing properties through increased wound breaking strength, reduced glutathione, decrease percentage of wound area, scar area and lipid peroxidation. Wound healing was probably through antioxidant effect and various biochemical parameters. †¢ Anti-Ulcer  Activity: Study of dried powder of banana pulp showed anti-ulcerogenic activity, esp in the unripe, mature green plantain banana (var. paradisiaca). †¢ Banana Peels Phytochemicals: Study showed the peel can be a good source of carbohydrates and fiber. The study of anti-nutrients showed generally low values except for saponins. Study suggests, properly processed and exploited, the peel could be a good source of livestock feed, providing a high quality and cheap source of carbohydrates and minerals. †¢ Antimicrobial Activity: (1) Study of ethanolic extracts of unripe bananas, lemon grass and turmeric showed antimicrobial activity at stock concentrations. Unripe bananas showed a high antimicrobial activity against all test organisms. (2) Ethanol extract of Musa sapientum showed antibacterial activity against the tested microorganisms – Gram-positive and Gram-negative bateria (B. subtilis, B. cereus, and E coli.) †¢ Anti-Helicobacter pylori / Anti-Internalisation Activity: In a study of 9 Thai plant extracts used for gastric ailments, Musa sapientum and Allium sativum showed marked anti-internalisation and present a potential benefit in H pylori , prevention eradication, therapy and avoidance of antibiotic resistance. †¢ Anticonvulsant: Study in mice showed AMS prevented convulsions possibly through prevention of inhibition of vitamin B6 metabolism with subsequent increase in GABA synthesis in the CNS or due to facilitatory effect on GABAergic neurons – an effect mediated by the antioxidant potential of phytoconstituents present in the AMS. †¢ Indigenous Antiulcer Activity / Leucocyanidin: Study investigated the anti-ulcerogenic activity of an aqueous extract of M. sapientum. Study yielded an active compound–a monomeric flavonoid, leucocyanidin, that showed anti-ulcerogenic activity, in congruous with standard drug esomeprazole. †¢ Antioxidant / Antibacterial /Hemagglutination Inhibition: Study of methanolic extract of leaves of M. sapientum var. Sylvesteris showed antioxidant and antibacterial activity in vitro. It also showed hemagglutination inhibition activities and hydrogen peroxide induced hemolysis inhibition activity of human red blood cells. †¢ Antimicrobial / Cytotoxicity: A methanolic extract of M. sapientum L subsp. sylvestris showed good antimicrobial activity the pulp, moderate activity with the peel, and insignificant activity with the seed. On cytotoxicity evaluation using Brine Shrimp Lethality, pulp>seed>peel.

Benefits of Integrating Human Resources Management (Hrm) and the Payroll Databases

Benefits of Integrating Human Resources Management (HRM) and the Payroll Databases. The Human Resources Management and Payroll are completely different business processes; however, they depend on each other for accurate and timely flow of information for their business operations. Integrating these two process will ensure that the information flow between them is timely and less erroneous. The benefits of such integration includes but not limited to: (a) No duplicate data entry: Integrating HRM and Payroll processes means maintaining a common database. Therefore, any changes made to any aspect of the database are entered only once. There will be no need to make a duplicate entry of the changes. This eliminates errors that may occur due to multiple entries. (b) Less paper work: Having a common database reduces unnecessary paperwork and greatly reduces input errors.  © Integrated Reporting: Integrating the HRM and Payroll makes room for automatic update of employees’ records. With integrated reporting tools, consolidated reporting can easily be generated and containing an up to date employee information, benefits, data, and compensation data. . The current problems related to labor at Fargo Publishing (a) Fargo Publishing still uses the traditional punch clocks to track employees’ time in and out of work. With this system, the company looses lots of money when employees arrive late to work, leave early from work, and then resort to â€Å"buddy clocking† that is clocking for other people. Employees are paid for hours not worked, and productivity is greatly affected. (b) Employees time data are manually inputted into the payroll computer by checking the time cards. The problem with this process is that there is high risk of input errors obtainable when manually inputting the data for 250 hourly workers. Manually inputting these data is time consuming and delays update to necessary master files.  © Too Many paper work: There is too many paper work involved in the flow of information among the different departments. Since the different processes at the Fargo publishing are not automated, a lot of paper work is involved in the flow of information from one department to the other. This process is not cost effective, and it is also time consuming. There could also be loss of data during transfer process. (d) Employees’ time cards are checked by HR on a weekly basis at the end of the week. This means that employee database is updated on a weekly basis as related to time in and out. Therefore, no report can be generated based on this information until the end of the week. The issue with this system occurs when there is any threat that will destroy the time cards before the end of the week, all data is lost because the master database is not updated. 3) Recommendations to improve the problems related to labor. a. The use of Biometric Time System: The biometric scan is an automated system that verifies employees’ identity based on their fingerprint. It provides a more reliable and accurate data on employees’ identity and time. It eliminates the problem of buddy clocking and ensures that employees are paid for time worked. b. Integration and Syn chronization of Databases: The use of Biometric Time Systems would require the integration and synchronization of all the databases in the HRM and Payroll departments. This will ensure immediate and accurate update to the common database, and easy back up following any changes. This system will also reduce the volume of paper work involved in processing the flow of information. c. The use of Input Edit and Processing Controls: At this point, I would recommend the use of Input Edit and Processing Controls to reduce and detect erroneous entry into the database. Example of controls include: Validity check and field (format) check. (4. ) How Management can measure the cost savings of these recommendations. A. The use of Biometric Time System: The cost savings can be measured by the volume of books printed per day as a result of employees having to report to work on time and leave at a scheduled time to personally clock in and out. The longer time employees spend at work, the more likely productivity will improve when properly supervised. B. Integration and Synchronization of databases: The cost savings can be measured by the amount spent on paper supplies at the end of every month. This is compare to when the system was not integrated or synchronized. It can also be measured by the ease of dataflow among departments, which is how long it takes for department to access information processed in another department. C. Input Edit and Processing Controls: The cost saving can be measured by the number of reports that have to be reproduced because of erroneous entries. It can also be measured by reduction in the overtime paid reflecting the extra hours put in to correct what was previously completed due to error. References Chestnut, R. (n. d). Traditional Punch Clocks Vs Biometric Time Systems. Retrieved November 16, 2010 from, http://www. ezinearticles. com/? Traditional-Punch-Clocks-Vs-Biometric-Time-Systems Romney, M. B. & Steinbart P. J. (2009). The Human Resources Management and Payroll Cycle. In Strayer University 2010 Custom Edition, Accounting Information Systems (pp. 497-517). Upper Saddle River, New Jersey: Prentice Hall. Sinh, M. (2010). Integrating HR and Payroll – Key Considerations and Benefits for Companies. Retrieved November 16, 2010 from, http://www. articlesbase. com/software-articles